Update from Oncology-Radiotherapy - Post 3

Sorry for the delayed reply. I have gone through the case and the following are my observations :

HME / HMO is a condition of benign recurrent bone tumours. Chance of malignant transformation is < 5% (mainly to osteo or chondrosarcomas).

A genetic testing for EXT1 and EXT2 should be done.

Surgery - repeated is the only known treatment with local excision preserving limb function as much as possible.

There is per se NO role of Radiation or Chemotherapy (and therefore of the Oncologist). Only if there is consequent malignant transformation, conclusively proven by biopsy with Immunohistochemistry, can an Oncological intervention be made.

My suggestion is to go ahead with surgery and a good Orthopaedic Surgical opinion beforehand.

Regards, 

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DR. ABHISHEK BASU
MBBS, MD, DNB (Radiotherapy), PDCR

Assistant Professor,
Department of Radiotherapy,
R. G. Kar Medical College & Hospitals,
Kolkata.
West Bengal, India.